Mevalonate Kinase (MVK) Peptide
MVK
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN940193
Quick Overview for Mevalonate Kinase (MVK) Peptide (ABIN940193)
Target
MVK
(Mevalonate Kinase (MVK))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- LAVLAFLYLY LSICRKQRAL PSLDIVVWSE LPPGAGLGSS AAYSVCLAAA
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of MVK antibody,
Alternative Names: MVK control peptide, MVK antibody Blocking Peptide, Anti-MVK Blocking Peptide, Mevalonate Kinase Blocking Peptide, LRBP Blocking Peptide, MVLK Blocking Peptide -
Purification
- The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide is removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- MVK (Mevalonate Kinase (MVK))
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Background
- MVK is the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash.
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Molecular Weight
- 42 kDa
Target
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